The surprise success of 2022’s Orphan: First Kill has opened the door for another sequel, and there are already exciting updates about Orphan 3. The series stars Isabelle Fuhrman as Esther, a murderous con woman who disguises herself as a nine-year-old girl. Serving as a prequel to Orphan, Orphan: First Kill was set a little over a decade before its predecessor. The movie was not exactly an origin story, but it did establish how she managed to escape a psychiatric facility in Estonia and head to the USA.